New DNA Nutrition Testing
We have a new test that I’m really excited about. It’s a DNA cheek swab that tests the function of over 1000 genes.
Most people don’t realize that nutrients from food are just raw materials. Everything our bodies need, every tissue of the body, and every metabolic function is based on nutrition. There is mounting evidence that underlying health problems can be traced to genetics and nutrition.
This genetic test offers customers a new perspective on their health. The test is offered through a nutrition office because genes and nutrients work together. Genetics testing provides a deeper insight into nutritional biochemistry how we can use nutrition to optimize health. (The majority of medical schools still don’t offer classes in nutrition, and this is a nutrition test.)
DNA Metabolism (number of genes checked 105)
This is a methylation pathway, where carbons are added to folate and redistributed to other compounds in the body. This is really important because it’s responsible for the formation of DNA, neurotransmitter function, detoxification, and many other processes. Recycling of carbons in methylation is critical for cell function, and these are located near the end of the 21 chromosome, making them more susceptible to mutations. Nutrient deficiencies can cause DNA problems. The nutritionist can support DNA metabolism.
Oxalate Metabolism (number of genes checked 32)
Everyone obtains oxalates from 3 sources: liver cells, yeast species and food. The degree to which an individual is predisposed to having adverse consequences from having high levels of oxalates is influenced by their ability to metabolize oxalates. Oxalates are a common cause of kidney stones but deposits can also occur in other critical places such as the brain and blood vessels. This can lead to pain, kidney problems and possibly neurological symptoms. The nutritionist can use diet and supplements to control the levels of yeast and or oxalates.
Mental Disorders/SAMe/B12 (number of genes checked 53)
The mental health panel identifies mutations to many of the genes that can influence mental health. Mutations to the genes can change the metabolism of neurotransmitters and increase the risk of developing depression, schizophrenia, anxiety and bipolar disorder. The nutritionist can support neurotransmitters with the right nutrients from specific foods and supplements. Brain risk factors can be reduced through the use of specific nutrition.
Gluten Opioid Peptide Homeostasis (number of genes checked 48)
The gluten sensitivity panel looks at a large portion of the genes that, if mutated, could lead to gluten sensitivity. Mutation in any of the genes in this pathway may indicate the need to limit or eliminate gluten from the diet. Gluten sensitivity can manifest in a variety of symptoms, particularly in the gut, brain and autoimmune systems. Many patients with chronic health conditions such as autism spectrum disorder report neurological benefits from switching to a gluten free diet.
Autism Spectrum Genes (number of genes checked 252)
Autism Spectrum Disorder (ASD) is a developmental disability characterized by unique cognitive and behavioral symptoms that vary in degree of severity. Multiple published studies have identified a series of genetic mutations that are more commonly found in patients with ASD than in the general population. Having one or more of these mutations doesn’t mean that the patient will develop ASD, but their risk for developing the disorder is higher than the general public. Specialized nutrition can support genes and metabolic pathways. Improving nutrition in these patients often reduces their symptoms.
P450s (cyps) Detoxification Metabolism (number of genes checked 241)
The cytochrome P450s are a family of monooxygenase enzymes that are expressed throughout the body but are mostly in the liver. They detoxify chemicals coming from outside of the body including medical drugs. They also metabolize chemicals that are inside of the body including hormones, neurotransmitters, cholesterol and vitamins. Mutations to P450s genes can alter the person’s ability to detoxify. Using this information can be used medically to help with appropriate prescription dosing, especially when a patient needs much less, or much more medication to have the same desired effect, such as in chemotherapy. Specialized nutrition can support genes, and has the potential to improve liver function.
Cholesterol Deficiency (synthesis/absorption/transport) (number of genes checked 101)
Cholesterol is an important molecule. It produces crucial hormones, vitamins, secondary messengers and bile acids. Low values are associated with depression, anxiety, suicide, violent behavior, bipolar disease, Parkinson’s disease, increased mortality from cancer. Low values are associated with a nutritional manganese deficiency, celiac disease, hyperthyroidism, liver disease, malabsorption and malnutrition. Proper nutrition can provide support to the genes along this pathway to normalize cholesterol metabolism.
Acetaminophen Toxification/Detoxification (number of genes checked 72)
Acetaminophen (Tylenol) is one of the most commonly used pain relievers. Proper metabolism of acetaminophen is critical to preventing toxicity and any resulting damage. Genetic mutations that cause an increase in the metabolite NAPQI and can limit the body’s ability to detoxify acetaminophen, making the person more susceptible to adverse effects of acetaminophen. Acetaminophen toxicity is the leading cause of liver failure, so checking genes before using this drug, and supporting the genes with nutrition, may be a good prevention strategy.
Transporters (number of genes checked 130)
Transported proteins are responsible for shuttling molecules across cell membranes. Mutations to transporter genes impede the ability of cells to uptake vital nutrients and export toxic substances. There are a number of diseases associated with faulty transport including Alzheimer’s disease, coronary artery disease, aggressive behavior, and decreased drug efficacy. Specialized nutrition can help support genes and improve cell membrane structure and function. This can optimize the movement of nutrients in and out of the cells.
If you’d like to look at your health from this new perspective, please call our office or visit our website, www.holisticnutritioncenter.net.